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I have had very good luck with DIGI port servers. We have many of these at facilities all over the world and they have worked flawlessly for us. The nice thing is, you can configure them so your LabVIEW code just connects over TCP/IP to their IP and the specific port that corresponds to the physical serial port on the unit. No need for any drivers on your machine. Of course, they also have a driver for virtual serial port support so existing apps can use them seamlessly. I know they come in 2,4 8 and 16 port versions. I have used the 4 and 16 port versions my self. They even have a wireless version if you don't have network cabling to where your serial device is located. You can remotely manage these via a web browser. here are some links: http://www.digi.com/products/serialservers/portserverts816.jsp#overview http://www.digi.com/products/serialservers/portserverts.jsp#overview good luck!