Report LabVIEW .NET interop assembly target framework in LabVIEW General Posted August 25 · Edited August 25 by Bobillier Hi pawhan11 Few days ago I have experiment one similar problem about exe and a .NET compoment (look here). I have solved it by adding a small file before my exe to indicate what assembly runtime version using. I'm not sure than you can use similar thing to solve your problem (LV11 refer natively to .NET 3.5), but perhaspse that can run. I have see something about that here Step 1: create a texte file named Labview.exe.config Step2: Place the text below in it <?xml version ="1.0"?> <configuration> <startup useLegacyV2RuntimeActivationPolicy="true"> <supportedRuntime version="v4.8"/> </startup> </configuration> Take care about supportedRuntime version number because it must be corresponding to your .NET constructor. Step3 : Save this file in same directory than your Labview version, and restart LabVIEW Step4 : Rebuild your assembly.