Hi lablc,
To set the boundaries of your front panel, go to File -> VI Properties -> Window Size and adjust the Width and Height parameters. Then, go to your front panel window (when it's not running) and shrink it as much as you can. It should not let you shrink it past the settings you entered.
From my experience, auto-scaling front panels in LabVIEW rarely produces good results. I always set the boundaries of my front panel first (in your case you would need to find the parameters that cause the panel to fit the screen for your resolution) and then I start developing the UI accordingly.
LP.