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I'm not familiar with network streams but the online help provides an example for your particular scenario (scroll to the very bottom): Specifying Network Stream Endpoint URLs - NI Based on your code this works for me: Working Example.zip Edit: To provide some more explanation: Only one application can create endpoints in the default (empty) context "//localhost/". Incidentally, this is also the default context when you create a writer endpoint by name. For example, writer endpoint "my_writer" is equivalent to "//localhost/my_writer". In your particular example, Application B creates a writer endpoint "ApplicationA_in_writer", which is equivalent to "//localhost/ApplicationA_in_writer". Application C creates a writer endpoint "ApplicationB_in_writer", which is equivalent to "//localhost/ApplicationB_in_writer". And since only one application can use the default context, the error happens. To create endpoints in separate contexts, you must specify the context in the endpoint name. For example, "//localhost:ApplicationB/ApplicationA_in_writer" and "//localhost:ApplicationC/ApplicationB_in_writer".