I already find 2009 to be less than it should stability-wise. This news about 2010 makes me wary.
If I may plug an idea of mine on the dark side....
Shane
I upgraded on one system (the other was clean) with a few LabVIEW versions on it and it worked fine. I think MS worked hard to make up grading easy this time. Of course the safest approach would be to image the system so that you can roll back if something goes wrong.